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[(Fig._1)TD$FIG]

Fig. 1 – Molecular subtypes in pre-NAC TURBT samples in discovery NAC cohort. (A) Overview of four previously described bladder cancer subtyping

methods. UNC divides the cancers in two classes, luminal and basal. Claudin

[6_TD$DIFF]

-low is a subtype within basal that has lost epithelial differentiation and

has a high level of immune infiltration. The MDA subtyping method also divides into basal and luminal tumors, in addition to a third subtype with an

E U R O P E A N U R O L O G Y 7 2 ( 2 0 1 7 ) 5 4 4 – 5 5 4

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