[(Fig._1)TD$FIG]
Fig. 1 – Molecular subtypes in pre-NAC TURBT samples in discovery NAC cohort. (A) Overview of four previously described bladder cancer subtyping
methods. UNC divides the cancers in two classes, luminal and basal. Claudin
[6_TD$DIFF]
-low is a subtype within basal that has lost epithelial differentiation and
has a high level of immune infiltration. The MDA subtyping method also divides into basal and luminal tumors, in addition to a third subtype with an
E U R O P E A N U R O L O G Y 7 2 ( 2 0 1 7 ) 5 4 4 – 5 5 4
547




