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recommendations are to estimate life expectancy based on

the combination of age and comorbidity

[22,23]

. Therefore,

the choice remains pragmatic and open to debate. However

for future research better tools are desirable. It is vital that

decision-making is shared with patients and that they

receive detailed information, including assessment of

potential risks and benefits

[24] .

Health status in SIOG guidelines has generally been

defined according to groups described by Balducci and

Extermann in 2000

[25] .

These revised prostate cancer

guidelines classify patients into four groups (the terminol-

ogy now aligns with that in the geriatric literature) along

with the implications for treatment

( Figs. 1 and 2 )

.

(1)

Healthy or fit:

G8 score

>

14. Patients are expected to

tolerate any form of standard treatment. The choice of a

particular local treatment is then based on the patient’s

wishes and the risk of specific side effects, such as

incontinence (described below), for each modality.

(2)

Frail:

patients with a G8 score 14 but whose problems,

as established via a simplified geriatric assessment

(CIRS-G, ADL, and malnutrition), are considered revers-

ible. Such problems are: one or two reversible

deficiencies in ADL (apart from incontinence); CISR-G

grade 2 comorbidities (a single grade 3 comorbidity

may also be reversible); and weight loss of 5–10%.

Patients whose problems are reversed can be consid-

ered fit for standard prostate cancer therapies.

(3)

Disabled or with severe comorbidities

: nonreversible

problems. These include more than two ADL deficien-

cies; multiple grade 3 comorbidities on the CISR-G or

any grade 4 comorbidity; or weight loss

>

10%. Such

patients should be managed symptomatically. Certain

patients may benefit from geriatric interventions

indicated after CGA and can be given specific adapted

cancer treatments.

(4)

Terminally ill:

palliation only.

Two additional points should be made. First, in patients

who require a CGA, specific geriatric interventions may be

suggested. Second, if the mini-COG

[4_TD$DIFF]

TM

score is abnormal, a

full neuropsychological assessment is recommended.

Table 2 – The Mini-COG

[4_TD$DIFF]

TM

screening tool

[6_TD$DIFF]

. Copyright S. Borson, reprinted with permission of the author

(soob@uw.edu

).

[12]

Step 1: Three words registration

Look directly at person and say, ‘‘Please listen carefully. I am going to say three words that I want you to repeat back to me now and try to remember. The words

are [select a list of words from the versions below]. Please say them for me now.’’ If the person is unable to repeat the words after three attempts, move on to

Step 2 (clock drawing).

The following and other word lists have been used in one or more clinical studies. For repeated administrations, use of an alternative word list is recommended.

Version 1

Version 2

Version 3

Version 4

Version 5

Version 6

Banana

Leader

Village

River

Captain

Daughter

Sunrise

Season

Kitchen

Nation

Garden

Heaven

Chair

Table

Baby

Finger

Picture

Mountain

Step 2: Clock drawing

Say: ‘‘Next, I want you to draw a clock for me. First, put in all of the numbers where they go.’’ When that is completed, say: ‘‘Now, set the hands to 10 past 11.’’

Use a preprinted circle for this exercise. Repeat the instructions as needed, as this is not a memory test. Move to Step 3 if the clock is not complete within 3 min.

Step 3: Three words recall

Ask the person to recall the three words you stated in Step 1. Say: ‘‘What were the three words I asked you to remember?’’ Record the word list version

number and the person’s answers.

Scoring

Word recall: ______ (0–3 points)

=1 point for each word spontaneously recalled without cueing.

Clock draw: ______ (0 or 2 points)

=Normal clock: 2 points. A normal clock has all numbers placed in the correct sequence and approximately correct position (eg, 12, 3, 6, and 9 are in anchor

positions) with no missing or duplicate numbers. Hands are pointing to the 11 and 2 (11:10). Hand length is not scored.

Inability or refusal to draw a clock (abnormal) = 0 points.

Total score: ______ (0–5 points)

=Total score: word recall score + clock draw score.

A cut point of

<

3 on the Mini-COG

[4_TD$DIFF]

TM

has been validated for dementia screening, but many individuals with clinically meaningful cognitive impairment will

score higher. When greater sensitivity is desired, a cut point of

<

4 is recommended as it may indicate a need for further evaluation of cognitive status.

Table 3 – Summary of the different steps in health status evaluation and estimated time required

Step

Tools

Time

Who can do it?

Mandatory initial step

G8

Mini-COG

[7_TD$DIFF]

TM

5 min

5 min

Trained nurse

Trained nurse

Simplified geriatric evaluation if G8 score is 14 ADL

CIRS-G

Weight loss

1 min

15 min

1 min

Trained nurse

Trained nurse and/or doctor

Trained nurse

Comprehensive geriatric assessment if geriatric

intervention needed

Screening tools and complete

clinical examination

2 h to 1 d in hospital

Geriatrician + other health professionals

E U R O P E A N U R O L O G Y 7 2 ( 2 0 1 7 ) 5 2 1 – 5 3 1

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