recommendations are to estimate life expectancy based on
the combination of age and comorbidity
[22,23]. Therefore,
the choice remains pragmatic and open to debate. However
for future research better tools are desirable. It is vital that
decision-making is shared with patients and that they
receive detailed information, including assessment of
potential risks and benefits
[24] .Health status in SIOG guidelines has generally been
defined according to groups described by Balducci and
Extermann in 2000
[25] .These revised prostate cancer
guidelines classify patients into four groups (the terminol-
ogy now aligns with that in the geriatric literature) along
with the implications for treatment
( Figs. 1 and 2 ).
(1)
Healthy or fit:
G8 score
>
14. Patients are expected to
tolerate any form of standard treatment. The choice of a
particular local treatment is then based on the patient’s
wishes and the risk of specific side effects, such as
incontinence (described below), for each modality.
(2)
Frail:
patients with a G8 score 14 but whose problems,
as established via a simplified geriatric assessment
(CIRS-G, ADL, and malnutrition), are considered revers-
ible. Such problems are: one or two reversible
deficiencies in ADL (apart from incontinence); CISR-G
grade 2 comorbidities (a single grade 3 comorbidity
may also be reversible); and weight loss of 5–10%.
Patients whose problems are reversed can be consid-
ered fit for standard prostate cancer therapies.
(3)
Disabled or with severe comorbidities
: nonreversible
problems. These include more than two ADL deficien-
cies; multiple grade 3 comorbidities on the CISR-G or
any grade 4 comorbidity; or weight loss
>
10%. Such
patients should be managed symptomatically. Certain
patients may benefit from geriatric interventions
indicated after CGA and can be given specific adapted
cancer treatments.
(4)
Terminally ill:
palliation only.
Two additional points should be made. First, in patients
who require a CGA, specific geriatric interventions may be
suggested. Second, if the mini-COG
[4_TD$DIFF]
TM
score is abnormal, a
full neuropsychological assessment is recommended.
Table 2 – The Mini-COG
[4_TD$DIFF]
TM
screening tool
[6_TD$DIFF]
. Copyright S. Borson, reprinted with permission of the author
(soob@uw.edu).
[12]Step 1: Three words registration
Look directly at person and say, ‘‘Please listen carefully. I am going to say three words that I want you to repeat back to me now and try to remember. The words
are [select a list of words from the versions below]. Please say them for me now.’’ If the person is unable to repeat the words after three attempts, move on to
Step 2 (clock drawing).
The following and other word lists have been used in one or more clinical studies. For repeated administrations, use of an alternative word list is recommended.
Version 1
Version 2
Version 3
Version 4
Version 5
Version 6
Banana
Leader
Village
River
Captain
Daughter
Sunrise
Season
Kitchen
Nation
Garden
Heaven
Chair
Table
Baby
Finger
Picture
Mountain
Step 2: Clock drawing
Say: ‘‘Next, I want you to draw a clock for me. First, put in all of the numbers where they go.’’ When that is completed, say: ‘‘Now, set the hands to 10 past 11.’’
Use a preprinted circle for this exercise. Repeat the instructions as needed, as this is not a memory test. Move to Step 3 if the clock is not complete within 3 min.
Step 3: Three words recall
Ask the person to recall the three words you stated in Step 1. Say: ‘‘What were the three words I asked you to remember?’’ Record the word list version
number and the person’s answers.
Scoring
Word recall: ______ (0–3 points)
=1 point for each word spontaneously recalled without cueing.
Clock draw: ______ (0 or 2 points)
=Normal clock: 2 points. A normal clock has all numbers placed in the correct sequence and approximately correct position (eg, 12, 3, 6, and 9 are in anchor
positions) with no missing or duplicate numbers. Hands are pointing to the 11 and 2 (11:10). Hand length is not scored.
Inability or refusal to draw a clock (abnormal) = 0 points.
Total score: ______ (0–5 points)
=Total score: word recall score + clock draw score.
A cut point of
<
3 on the Mini-COG
[4_TD$DIFF]
TM
has been validated for dementia screening, but many individuals with clinically meaningful cognitive impairment will
score higher. When greater sensitivity is desired, a cut point of
<
4 is recommended as it may indicate a need for further evaluation of cognitive status.
Table 3 – Summary of the different steps in health status evaluation and estimated time required
Step
Tools
Time
Who can do it?
Mandatory initial step
G8
Mini-COG
[7_TD$DIFF]
TM
5 min
5 min
Trained nurse
Trained nurse
Simplified geriatric evaluation if G8 score is 14 ADL
CIRS-G
Weight loss
1 min
15 min
1 min
Trained nurse
Trained nurse and/or doctor
Trained nurse
Comprehensive geriatric assessment if geriatric
intervention needed
Screening tools and complete
clinical examination
2 h to 1 d in hospital
Geriatrician + other health professionals
E U R O P E A N U R O L O G Y 7 2 ( 2 0 1 7 ) 5 2 1 – 5 3 1
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