EURURO Vol. 72 No. 4

597 656

Table 1 ( Continued )
Author Yr Animal
model
No. of
animals
Sex Surgical
procedure
(defect length
in mm)
Biomaterial
(category)
Type of added cells Quality
assessment +
meta-analysis
37 Fu Q 2007 Rabbit 18 M Full (15) BAM, rabbit (D) Autologous foreskin epidermal
cells
Yes
38 Fu Q 2008 Rabbit 18 M Full (15) BAM, rabbit (D) Autologous foreskin epidermal
cells
Yes
39 Gu GI 2012 Rabbit 18 M Full (15) BAM, rabbit (D) Autologous mesothelial cells Yes
40 Li CL 2013 Rabbit 30 M Full (30) BAM, rabbit (D) Autologous bone-marrow
derived MSCs and SMCs
Yes
41 Li B 2013 Rabbit 12 M Full (15) Frozen-thawed bladder
mucosa, dog (D)
— Yes
42 Kjaer TB 1976 Dog 9 M Full (30) Lyophilized vein, dog (D) — Yes
43 Shokeir A 2004 Dog 14 M + F Full (30) UAM, dog (D) — Yes
44 Sievert KD 2001 Rabbit 14 M Full (8–11) UAM, dog and rabbit (D) — Yes
45 Sievert KD 2000 Rabbit 30 M Full (8–11) UAM, rabbit (D) — Yes
46 Lv X 2016 Dog 18 F Full (20) Bacterial cellulose + potato
starch (N)
Dog lingual muscle cells Yes
47 Gu GI 2010 Rabbit 9 M Full (15) De-novo created tissue in
peritoneal cavity (N)
— Yes
48 Jia W 2015 Dog 10 M Full (50) Type I collagen scaffold + /-
3VEGF (N)
— Yes
49 A Da Silva LF 2014 Rabbit 16 M Full (10) Type I collagen, bovine (N) Autologous bladder SMCs Yes
50 Nuininga JE 2010 Rabbit 32 M Full (10) Type I collagen, bovine (N) — Yes
51 Kanatani I 2007 Rabbit 28 M Full (15) Type I collagen, porcine +
P(LA/CL) (N)
— Yes
52 Micol LA 2012 Rabbit 16 M Full (10) Type I collagen, rat tail (N) Autologous bladder SMCs Yes
53 Mikami H 2012 Dog 10 M Full (20) Type I collagen, rat tail (N) Autologous oral epithelial
and muscle cells
Yes
54 Italiano G 1997 Rabbit 14 M Full (15) Hyaluronan benzyl ester (S) — Yes
55 Italiano G 1998 Rabbit 4 M Full (15) Hyaluronan benzyl ester (S) — Yes
56 Fu Q 2014 Dog 18 M Full (15) PGA (S) Oral mucosal epithelial
cells and AdSCs
Yes
57 Hakky SI 1977 Dog 15 M Full (50) Polyethylene terephthalate (S) — Yes
58 Hakky SI 1977 Dog 9 M Full (50) Polyethylene terephthalate (S) — Yes
59 Olsen L 1992 Dog 6 M Full (30–40) Polyglactin fiber coated with
polyhydroxybutyric acid (S)
— Yes
60 Anwar H 1984 Dog 10 ? Full (25) PTFE (S) — Yes
61 Dreikorn K 1979 Dog 12 M Full (30–80) PTFE (S) — Yes
62 Xie H 2007 Rabbit 34 M Inlay + full (15) Elastin and collagen,
porcine (N)
— Yes
63 El-Assmy A 2004 Rabbit 18 M Inlay + full (15) SIS (D) — Yes
64 Wang YQ 2005 Rabbit 14 M Inlay (10) BAM, human (D) — No (CN
65 Beintker M 2007 Rat 20 M Inlay (?) SIS (D) — N
66 Glybochko PV 2014 Rabbit Unknown M Full (?) Acellular artery, human (D) — No (RU)a
67 Peng WB 2013 Rabbit Unknown M Full (25) BAM (D) Rabbit hair follicle
stem cells
No (CN)a
68 Hu YF 2008 Rabbit 30 M Full (10–15) UAM, rabbit (D) — N
69 Hu YF 2009 Rabbit 20 M Full (10–15) UAM, rabbit (D) — No (CN
70 Yang SX 2004 Rabbit 30 M Full (10–15) UAM, rabbit (D) — N
71 Lebret T 1994 Rat 7 F Full (?) Type IV collagen, human (N) — N
72 Fu WJ 2009 Rabbit 32 M Full (10–15) PLLA (S) Autologous urothelial
cells
N
73 Verit A 2003 Dog 2 M Full (10) PTFE (S) — No (TR
74 Huang X 2006 Rabbit 12 M Inlay + full (?) SIS, porcine (D) — No (CN
75 Fu Q 2006 Rabbit 12 M Unclear (10–30) BAM, rabbit (D) — No (CN
76 Xu LS 2007 Rabbit 48 M Unclear (?) UAM, porcine (D) — N
77 Han P 2009 Rabbit 24 M Unclear (20) UAM, rabbit (D) Rabbit bladder SMCs No (CN
78 Huang HJ 2007 Rabbit 48 M Unclear (?) UAM, rabbit (D) Rabbit bone marrow
derived MSCs
No (CN
79 Zhang Y 2011 Rabbit Unknown M Unclear (?) Silk fibroin (N) Rabbit AdSCs No (CN
80 Liu C 2008 Dog 12 M Unclear (15–30) Silk fibroin (N) — No (CN
? = unclear; AdSC = adipose-derived stem cells; BAM = bladder acellular matrix; CN = Chinese; D = decellularized; F = female; M = male; MSC = mesenchymal
stem cells; N = natural; P(LA/CL) = copoly(L-lactide/e-caprolactone); PTFE = polytetrafluoroethylene; RU = Russian; S = synthetic; SIS = small intestinal
submucosa; siRNA = small interfering RNA; SMC = smooth muscle cell; TGF-b = transforming growth factor-b; TR = Turkish; UAM = urethral acellular matrix;
VEGF = vascular endothelial growth factor.
a Excluded from meta-analysis due to language restrictions defined in Section .
b Excluded from meta-analysis because only two studies used rats (insufficient for statistical analysis).
c Excluded from meta-analysis due to unclear experimental setup.
E U R O P E A N U R O L O G Y 7 2 ( 2 0 1 7 ) 5 9 4 – 6 0 6 597