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Advertising Feature

Supported by Boston Scientific

The GreenLight XPS™ Laser Therapy System redefines the standard

of care for safe and effective treatment of BPO

In recent years, the use of novel laser treatments for patients

with benign prostatic obstruction (BPO) has consistently

been on the rise, meeting the increasing demand for mini-

mally invasive surgical procedures (after failure of medical

therapy) which offer shorter hospitalization times as well as

faster mobilization and recovery. Dr. med. Claus Brunken,

Head of the Urology Department at the Asklepios Westklini-

kum in Hamburg, Germany, discusses the different minimal-

ly invasive transurethral BPO treatment options currently

available and shares his expertise with the GreenLight XPS™

Laser Therapy System and its impact in clinical practice.

Dr. Brunken, how long have you been using the

GreenLight XPS™ Laser System?

I have conducted approximately 1,000 GreenLight laser pro-

cedures within the last ten years. Along with the holmium

laser for transurethral enucleation, GreenLight has become

a specialty at our clinic, where we currently perform approxi-

mately 100 to 120 laser procedures per year. However, since

the prevalence of BPO increases with age, the number of

BPO treatments is set to rise as a result of aging societies.

Today, symptomatic BPO is the most common reason for

lower urinary tract symptoms (LUTS) and has a global preva-

lence of 50% to 60% among men in their 60s.

1

In your experience, what is the tangible impact of BPO

on patients’ lives?

Studies have shown that the perceived burden of disease for

men with BPO is high – sometimes it is even comparable to

the burden associated with malignant diseases. In addition

to sleepless nights resulting from nocturia, everyday outings

such as shopping or going to the cinema become difficult

due to common symptoms like urge incontinence and other

lower urinary tract symptoms. This indicates a significantly

reduced quality of life not only for patients but also for their

partners.

These everyday restrictions are particularly frustrating for

patients considering their increasingly high expectations

regarding quality of life. In contrast to 20 years ago, it is now

the norm for men in their 70s to expect to lead the same

active lifestyle as men in their 60s. Patients want to leave

hospital as soon as possible and often the first question they

ask post-surgery is how quickly they can take up sport again.

The consequences for BPO treatment are significant; ideally,

procedures should be as minimally invasive as possible with

short catheterization time, allowing patients to quickly return

to the active lifestyle they strive for.

Today, urologists can select from a broad range of differ-

ent laser techniques which complement TURP (transure-

thral prostate resection) as the current standard of care

in BPO treatment.What are the benefits of novel laser

systems in clinical practice?

Having a variety of different laser systems enables us to select

the most appropriate treatment for each patient’s needs,

adapting treatment to the individual profile and thus poten-

tially improving patient outcomes. This is particularly impor­

tant considering pre-existing conditions, current medication

(especially anticoagulants) and prostate size. At our clinic,

we offer both transurethral enucleation with the Holmium

(HoLEP) and transurethral vaporization with the GreenLight

laser to cater for different prostate sizes. We use the

GreenLight laser vaporization under consideration of the

patient’s general condition for small to larger prostate glands.

Normally, patients with relevant comorbidities are directly

referred to us for treatment with the GreenLight laser, since

this is often considered the most suitable option for these

patients. However, all laser systems enable a minimally inva-

sive procedure with comparable clinical results to the current

standard of care.

Which patients are particularly eligible for GreenLight

laser treatment?

Patients who need a surgical BPO therapy approach and

who have a high bleeding risk, e.g. due to receiving anticoag-

ulation therapy, are generally indicated for GreenLight laser

treatment due to the excellent hemostatic effect achieved

during the procedure. Moreover, the lower volumes of irriga-

tion fluid necessary and the low fluid intake with GreenLight

also make the procedure less strenuous. This also makes

GreenLight a suitable and established option for elderly or

frail patients with comorbidities, cardiac or other pre-existing

conditions, simply because the procedure has a favorable

risk profile and is less demanding for such patients than the

standard TURP procedure. Due to the rising life expectancy

and improved medical therapy options, we see an increasing

number of this patient type in clinical practice.

Dr. med. Claus Brunken, Head of the Urology Department at the Asklepios

Westklinikum in Hamburg, Germany