FM7 656
e u r o p e a n u r o l o g y , vo l . 7 2 , n o . 4 , Oc t o b e r 2 0 1 7
544
Impact of Molecular Subtypes in Muscle-invasive Bladder Cancer on Predicting Response and Survival after Neoadjuvant ChemotherapyR. Seiler, H.A.D. Ashab, N. Erho, B.W.G. van Rhijn, B. Winters, J. Douglas, K.E. Van Kessel,
E.E. Fransen van de Putte, M. Sommerlad, N.Q. Wang, V. Choeurng, E.A. Gibb,
B. Palmer-Aronsten, L.L. Lam, C. Buerki, E. Davicioni, G. Sjödahl, J. Kardos, K.A. Hoadley,
S.P. Lerner, D.J. McConkey, W. Choi, W.Y. Kim, B. Kiss, G.N. Thalmann, T. Todenhöfer, S.J. Crabb,
S. North, E.C. Zwarthoff, J.L. Boormans, J. Wright, M. Dall’Era, M.S. van der Heijden, P.C. Black
Molecular subtypes in muscle-invasive bladder cancer appear have an impact on
patient response to neoadjuvant chemotherapy (NAC); namely, patients with basal
tumors showed the most benefit from NAC and should be prioritized for NAC.
Moreover, these subtypes can be identified in a single sample by our discovered
classifier.
555
Neoadjuvant Chemotherapy in Muscle-invasive Bladder Cancer: Are Things Now Getting Personal?M.D. Galsky, J.P. Sfakianos, B.S. Ferket
557
Evolution of Circulating Tumor DNA Profile from First-line to Subsequent Therapy in Metastatic Renal Cell CarcinomaS.K. Pal, G. Sonpavde, N. Agarwal, N.J. Vogelzang, S. Srinivas, N.B. Haas, S. Signoretti,
B.A. McGregor, J. Jones, R.B. Lanman, K.C. Banks, T.K. Choueiri
Collection of circulating tumor DNA is feasible in patients with metastatic renal cell
carcinoma, and analysis of a large cohort demonstrates significant changes in
circulating tumor DNA profile across patients’ clinical course which may have
therapeutic implications.
565
Applying Precision Oncology to Renal Cell Carcinoma: Emerging ChallengesJ.T. Leppert
567
Updated Systematic Review and Meta-analysis of the Comparative Data on Colposuspensions, Pubovaginal Slings, and Midurethral Tapes in the Surgical Treatment of Female Stress Urinary IncontinenceF. Fusco, M. Abdel-Fattah, C.R. Chapple, M. Creta, S. La Falce, D. Waltregny, G. Novara
The present analysis confirms the superiority of midurethral sling over Burch
colposuspension. The studies comparing insertion of retropubic tension-free vaginal
tapes and transobturator tension-free vaginal tapes (TO-TVT) showed higher subjective
and objective cure rates for the retropubic tension-free vaginal tapes but at the cost of
higher risks of some complications and voiding lower urinary tract symptoms. Efficacy
of inside-out and outside-in techniques of TO-TVT insertion was similar, although the risk
of vaginal perforation was lower in the inside-to-out TO-TVT.
592
Surgical Treatment of Female Stress Urinary Incontinence: Do Tapes Stand the Test of Time?F. Van der Aa, J. Deprest, D. De Ridder
594
Tissue Engineering of the Urethra: A Systematic Review and Meta-analysis of Preclinical and Clinical StudiesL.R.M. Versteegden, P.K.J.D. de Jonge, J. IntHout, T.H. van Kuppevelt, E. Oosterwijk, W.F.J. Feitz,
R.B.M. de Vries, W.F. Daamen
Our comprehensive systematic review and meta-analysis shows potential for the
use of tissue engineering for urethra reconstruction. However, improvements in
preclinical and clinical study designs are essential to further stimulate clinical
translation of tissue engineering as an alternative for autografts.
607
Tissue Engineering of the Urethra: Solid Basic Research and Farsighted Planning are Required for Clinical ApplicationK.-D. Sievert
Urothelial Cancer
Female Urology –
Incontinence
Kidney Cancer
Reconstructive
Urology